Polynucleotides, including Newest, Plinest, and Plinest Eye, are innovative treatments in aesthetic medicine that enhance skin health and reduce the appearance of wrinkles and other signs of aging. These treatments, developed by Mastelli, use patented polynucleotides (PN-HPT®) that offer long-term hydration and help restore volume to the skin, promoting natural self-renewal and collagen production.

Plinest® is the latest solution for stimulating the natural regeneration of younger skin, while Newest® is used for the natural regeneration and rejuvenation of mature skin. Both products use patented polynucleotides PN-HPT®, with Newest® additionally containing hyaluronic acid and mannitol to enhance hydration and prolong its effects.

The polynucleotide treatment begins with disinfection and cleaning of the skin, followed by the application of topical anesthesia. The material is then injected into the skin with fine needles. The procedure is not painful, and results are visible after a few days. It is recommended to repeat the treatment every month, 2-3 times.

Polynucleotides have the ability to stimulate the synthesis of collagen and elastin, which are key elements for skin elasticity, firmness, and a healthy appearance. These molecules help in hydrating the skin, improving its texture and tone, and reducing hyperpigmentation and wrinkles. Additionally, polynucleotides are used in skin regeneration after damage such as burns.

A polynucleotide cocktail is a cosmetic product used in aesthetic medicine for skin care and reducing signs of aging. It consists of nucleotide bases, amino acids, and other ingredients that stimulate the production of collagen and elastin. The treatment is non-invasive, administered in aesthetic clinics, and results include reduced wrinkles and improved overall skin condition.